Potencialidad antifúngica de Guazuma ulmifolia frente a Fusarium oxysporum

Abstract

The present research focused on determining the antifungal potential of the Guazuma ulmifolia species, located in the department of Tolima, establishing its inhibitory effect against Fusarium oxysporum, a phytopathogenic fungus that affects horticultural, fruit and flower crops. The methodology included the approach to the chemical identity of the species through qualitative methods (preliminary phytochemical study and tentative identification of compounds by gas chromatography coupled to mass spectrometry) and quantitative methods (quantification of total phenols and flavonoids). In this sense, the presence of secondary metabolites such as phenolic compounds, flavonoids, terpenes, quinones, tannins, carotenoids, alkaloids were preliminarily determined and the presence of cardiotonics in this plant species was reported for the first time. In addition, a study was carried out to evaluate its antifungal was also carried out to evaluate its antifungal activity using the poisoned medium methodology, in which the extracts (ethanolic) and fractions (hexane, dichloromethane and ethyl acetate) of the leaves of G. ulmifolia species were evaluated, dichloromethane and ethyl acetate) of the leaves of G. ulmifolia species were evaluated at concentrations of 5000, 3000, 3000, 3000, 3000, 3000 and 3000 concentrations of 5000, 3000, 2000, 2000, 1500, 1000, 500 and 250 mg/L, obtaining favorable results in the inhibition of the the mycelial growth inhibition, highlighting the ethyl acetate fraction of the the ethyl acetate fraction which shows the highest inhibition, since it shows a %ICM of 95.44%. of 95.44% and an IC50 of 47.76 mg/L, which can be attributed to high contents of phenolic compounds and flavonoids, among other secondary metabolites that provide biological activity to the plants.