Modelo numérico de la respuesta óptica de una nanopartícula polimérica sumergida en un medio acuoso

Abstract

This paper presents the results of a numerical model that allows the separation of the absorption and scattering spectra of light interacting with polymeric nanoparticles, manufactured to be used in the transport and release of drugs in the treatment of cancer-related pathologies. Data from the characteristic spectra of nanoparticles synthesized by the reprecipitation method manufactured by Ramos and collaborators were used. These nanoparticles are found in an aqueous medium and when interacting with electromagnetic radiation, two basic processes occur: absorption and scattering. Separating both parts of the spectrum is necessary to understand the optical response of the nanoparticles and thus determine the extinct radiation that is presented as an artifact in the absorption spectra generated experimentally. Likewise, the numerical model proposed here is contrasted with experimental data obtained from nanoparticles fabricated by the reprecipitation technique.