Estudio de evaluación dosimetrica in vivo en la técnica de irradiación corporal total con arcoterapia volumétrica modulada con detectores Mosfet

Abstract

Total body irradiation (TBI) with megavoltage photon beams has been accepted as an important component of the treatment of malignancies involving the blood, bone marrow, and lymph nodes. The objective of the treatment is to guarantee that the prescribed dose is administered with a homogeneity in the patient, in addition to killing malignant cells, TBI helps prevent the immune system from rejecting the transplant treatment, in the particular case of bone marrow transplant . This treatment can be performed with different techniques; The most conventional way to apply TBI is by placing the patient standing or lying on their side several meters from the source, using static irradiation fields, only that this type of treatment has different drawbacks, one option to solve these problems is the implementation of TBI with intensity modulated radiation field arc therapy[9], avoiding the need for personalized shielding and short treatment distances (without the need for complex configurations for treatment), however this implies implementing different immobilization systems of patients. To carry out a TBI procedure with intensity-modulated volumetric arc therapy, it is previously necessary to perform in vivo dosimetry, which allows verifying the dose received by a patient, detecting under- or over-dosing at the beginning or during the radiotherapy process. In order to guarantee the efficiency of the system, it is necessary to use radiation detectors which are classified into gaseous detectors, semiconductor detectors and field effect transistors [9]. In the following work, the possibility of using radiation detectors will be examined. field, specifically MOSFETs for in vivo dosimetry in total body radiation technique with intensity modulated volumetric arc therapy