Estudio por dinámica molecular browniana de nanopartículas bajo efecto de un campo magnético externo

Abstract

In this work the results of the simulation by means of the Brownian molecular dynamics technique of the trajectory of magnetic nanoparticles present in the bloodstream are shown taking into account magnetic fields and random collisions with the formed elements that make up the blood. The blood vessel is considered as a cylindrical tube, with radial symmetry and constant laminar flow. The nanoparticle is injected into the bloodstream near the target zone along the vessel to be directed by external magnetic fields generated by permanent magnets, the magnetic field lines are oriented perpendicular to the blood flow. All those forces that are expected to significantly affect the transport of the nanoparticle are taken into account, such as the magnetization force, the drag force and the random force generated from the nanoparticle collisions. It is determined that when larger collisions occur, the nanoparticles deviate from the path in which these conditions are not taken into account, this because the random force produces a change in the angle that directs the nanoparticle, causing a variation in its speed and therefore in position.