Efectos de la interacción de partículas cargadas con tejidos biológicos

Abstract

The study of the effects of ionizing radiation dates back to the late 1800's, and represents great advances in medicine, radiotherapy and science, such as the discovery of X-rays and the first radiography. This type of radiation interacts with matter through different physical mechanisms causing diverse effects at the biophysical level. There are several ways to study such effects produced by the interaction of particles with biological tissues, including theoretical developments, experimental and computational data collection. This paper provides the biophysical fundamentals that allow characterizing the physical variables deposited energy and LET for electrons and protons when they are made to impinge on two materials: water and brain. For this purpose, a computational simulation was implemented to elaborate a comparison between the computationally generated data for protons and electrons. data generated computationally for protons and electrons and those extracted from various bibliographic sources. Once the theoretical part was interpreted and the results obtained, a discussion and analysis was developed through a state of the art regarding the effects of the interaction of charged particles with biological tissues and the final conclusions.